RF Exposure Measurement System for Biological Media Using Multiple Optimized SAR Distributions

The objective of this work is to develop and optimize a system to evaluate the effects of RF exposure on biological cell cultures, operating at a wide range of frequencies using multiple specific absorption rate (SAR) distributions simultaneously. In-vitro RF exposure measurements are time-consuming, and in order to show meaningful statistical results, multiple measurements are required. Additionally, many parameters may have to be varied to evaluate the effects of frequency, dosimetry, time, etc., leading to a long series of measurements that can be quite time consuming. Here, we propose a system that is able to achieve multiple optimized SAR distributions by varying the dosage of the cell culture medium in each well of a multi-well plate. Additionally, the setup avoids any resonating modes by using RF absorbers placed around the antenna and the multi-well plate, making it functional at a wide range of frequencies.