Wireless Reconfigurable RF Detector Array for Focal and Multiregional Signal Enhancement

Wirelessly Amplified NMR Detectors (WAND) can utilize wireless pumping power to amplify MRI signals in situ for sensitivity enhancement of deep-lying tissues that are difficult to access by conventional surface coils. To reconfigure between selective and simultaneous activation in a multielement array, each WAND has a dipole resonance mode for MR signal acquisition and two butterfly modes that support counter-rotating current circulation. Because detectors in the same row share the same lower butterfly frequency but different higher butterfly frequency, a pumping signal at the sum frequency of the dipole mode and the higher butterfly mode can selectively activate individual resonators, leading to 4-fold sensitivity gain over passive coupling. Meanwhile, a pumping signal at the sum frequency of the dipole mode and the lower butterfly mode can simultaneously activate multiple resonators in the same row, leading to 3-fold sensitivity gain over passive coupling. When multiple rows of detectors are parallelly aligned, each row has a unique lower butterfly frequency for consecutive activation during the acquisition interval of the others. This wireless detector array can be embedded beneath a headpost that is normally required for multi-modal brain imaging, enabling easy reconfiguration between focal imaging of individual vessels and multiregional mapping of brain connectivity.