Preliminary Investigation of an AdaptiSPECT-C Design with Rotated Square and Hexagonal Detectors

AdaptiSPECT-C (ASC) is being designed as an adaptive multi-pinhole SPECT imaging system with multiple detectors arranged in sphere-like geometry in three rings (Caudal, Middle, and Quasi-Vertex (QV)). Herein we investigate the usage of rotated square detectors for the first two rings, and hexagonal detectors for QV ring. We compare designs for different levels of temporal shuttering of the multiple apertures irradiating each detector. We assess image quality for a variety of phantoms assessing uniformity, axial sampling, and brain perfusion imaging. We determine that rotated square detectors can provide good uniformity, the axial sampling we have observed thus far based on reconstruction of a tailored Defrise Phantom and reconstructions of the brain phantom modeling perfusion distribution.