Definition and Usage of Texture Feature for Biological Sequence

In recent years, sequencing technology has developed rapidly. This produces a large number of biological sequence data. Because of its importance, there have been many studies on biological sequences. However, there is still a lack of an effective quantitative method for defining and calculating texture features of biological sequences. Texture is an important visual feature. It is generally used to describe the spatial arrangement of intensities of images. Here we defined the texture features of biological sequence. Combining the digital coding of biological sequence with the calculation method of image texture features, we defined the texture features of biological sequence and designed the calculation method. We applied this method to DNA sequence features quantification and analysis. Using these quantified features, we can compute the similarity distance matrix of DNA sequences and construct the phylogenetic relationships based on the clustering of the quantified features. This method can be applied to analyze any biological sequence, and all biological sequences can be digitally coded and texture features can be calculated by this method. This is a novel study of biological sequence texture features. This will usher in a new era of quantitative and mathematical calculation of biological sequence features.