High-Frequency Oscillations in Epilepsy: A Short Review

High-Frequency Oscillations (HFOs) are current strong candidates to serve as biomarkers for the seizure-onset zone (SOZ) in epilepsy. The emergence of new technology and digital methods benefits epilepsy research with the identification and characterizing the SOZ by using HFOs. Invasive recordings, together with automatic detection methods, are at the forefront of epilepsy research, especially when surgery is inevitable for seizure-freedom. However, recent non-invasive HFOs recordings quickly gathered attention for validation to be implemented in future clinical research and practice. This short review aims to briefly provide the research findings regarding HFOs and their significance as biomarkers of epileptogenicity.