Four-Input Multi-Layer Majority Logic Circuit Based on DNA Strand Displacement Computing

Biomolecules have the advantage of high performance parallel computing and large information capacity. The use of biochemical circuits to solve computational problems has been studied by many researchers. In this paper, we use DNA strand displacement technology to construct complex molecular circuits as logic gates. The experimental process is demonstrated by a series of strand displacement reactions, and the feasibility of the design is verified by the strand displacement simulation platform Visual DSD. The key feature of this logic gate design is that when two inputs of the same signal are controlled, the remaining two different input signals implement AND and OR function to determine the output. Based on this feature, a four-input multi-layer logic circuit is designed and implemented. The calculation mode of the other three inputs AND and OR combinations is implemented by controlling each logic gate input.