Frontal QRS-T Angle Measurement in Mice

Spatial QRS-T angle is an independent predictor of cardiac events. Wide QRS-T angle is correlated to fatal arrhythmias. The frontal QRS-T angle is the projection of the three-dimensional spatial angle into the frontal plane. This study aimed to develop a sistem that recorded the frontal ECG leads from mice. The frontal QRS-T angle was then derived from those leads. The ECG was acquired by using 3 analog modules which then digitized by microprocessor at 1000 samples/sec. The QRS-T angle calculation was implemented in Matlab to speed up the calculation process. The system was tested to measure a wistar rat of 2 months old. The results showed that QRS angles were quite stable compared to the T angles. Variation in the QRS-T angles was dominated by the T angles. The average QRS-T angle was 31.3°±8.04°.