Abstract:
Long read sequencing is promising as it provides knowledge of a full spectrum of mutations in the human genome and generates more contiguous de novo assemblies. But high ...Show MoreMetadata
Abstract:
Long read sequencing is promising as it provides knowledge of a full spectrum of mutations in the human genome and generates more contiguous de novo assemblies. But high error rate in long reads imposes a computational barrier for genome assembly. Darwin, a specialized coprocessor, which provides orders of magnitude speedup over conventional processors in long read assembly, can eliminate this barrier.
Published in: IEEE Micro ( Volume: 39, Issue: 3, 01 May-June 2019)