Ultra-Short Microwave Pulse Induced Thermoacoustic Therapy for Deep-Seated Tumor with Mitochondria-Targeting Single Wall Carbon Nanotubes

This study developed a deep-seated tumor therapy modality with mitochondria-targeting single-walled carbon nanotubes (SWNTs) as microwave absorbing agents, which high-efficiently convert ultra-shot microwave pulse energy into thermoacoustic (TA) shock wave and selectively destroy the targeted mitochondria, thereby inducing cancer cell apoptosis.