Inference of Gene Regulations Between Multiple Activators/Inhibitors and Singular Genes

A gene regulatory relation often has multiple activators or inhibitors. But most of current methods only focus on inferring gene regulatory relationships between two genes. We developed a new qualitative method for representing dynamic gene regulatory relations, and algorithms for identifying gene regulations with multiple regulators. All the algorithms are implemented in a program called GeneNetFinder (http://wilab.inha.ac.kr/genenetfinder) and tested on several gene expression data. The approach and the program would be useful for identifying gene regulations with multiple activator/inhibitors.