LA-iQID: A novel high-resolution CCD-based gamma camera for lymphatic imaging

iQID is an intensified quantum imaging detector developed at the Center for Gamma-Ray Imaging, University of Arizona. Based on the combination of a columnar scintillator, image intensifier, relay lens and fast-frame-rate CCD/CMOS sensor, iQID features ultra-high spatial resolution (<;100 μm), versatility, portability, and photon-counting capability. Originally developed for preclinical imaging, iQID cameras have been successfully used in small-animal scintigraphy, SPECT imaging, and particle imaging. As the first translation of iQID technology to clinical applications, this paper describes the design and development of a large-area iQID (LA-iQID) camera with sub-mm resolution performance and FOV of 188mm×188mm for dedicated point-of-care lymphatic imaging.