Design and Implementation of a Graphical User Interface for Dosimetry Calculation in Radiotherapy

There are several computer programs or combination of programs for radiation tracking, imaging and dosimetry in phantoms and inliving tissues. Among these some are based on GEANT4 programs whichare provided as classes that can be incorporated in C++ codes to achieve differenttasks in radiation interactionswith matter. GEANT4 made the physics easier but the programming remains a tedious task even for physicists familiar with computer programming while it is obviously out of reach of biological and clinical researchers. The aim of the present work was to report the design and development of a new interface GEANT4 Dose And Radiation Interactions (G4DARI) for absorbed dose calculation and for particle tracking in humans, small animals and phantoms. The calculation of the absorbed dose can be performed based on 3D CT images in DICOM format, from images of phantoms or from solid volumes which can be made from any pure or composite material to be specified by its molecular formula. As application, a lung tumor in a mouse irradiated with seven energy beams atdifferent angles and the absorbed dose was assessed in the tumor and in organs. In conclusion, G4DARI can be easily used by any researcher without the need to be familiar with computer programming, and it will be freely availablefor research.