Microfluidic Chip with Sandwich Structure for Terahertz Spectra of Glycerol

we adopt the microfluidic chip technique to detect liquid samples through THz- TDS system. The microfluidic chip has a sandwich structure which comprises cover, substrate and microchannel layer. The materials of cover and substrate is cycloolefin copolymers (zeonor 1420R), which has a very high transmittance for THz wave, and the microchannel layer is polydimethylsiloxane (PDMS). Through van der Waals force, the cover, substrate and microchannel layer are sealed together. The cover and substrate have the same thickness, that is, 1.5mm, and the length, width and depth of the microchannel are 30mm, 80um and 50um, respectively. The size of detection area of THz wave in the microchannel is 3.5mm in diameter. Using the microfluidic chip to detect the glycerol with a concentration of 98%, and the experimental results prove the feasibility of this method.