Neuropeptide Y Binding Dynamics Quantified with Nanophotonic Resonant Sensors

Nanostructured resonant sensors are used to record peptide binding dynamics. We quantify anti-NPY binding to NeutrAvidin and protein G and then NPY binding to anti-NPY. We report resonant wavelength shift of 160 pm for 8 pg/ml NPY with a detection limit of 1 μg/ml.