Classification of In Vitro Blood Stages of Plasmodium Falciparum Based on Fuzzy Inference System

This paper proposes the automated texture based classification of Malaria parasites in Giemsa-stained thin blood film images based on fuzzy inference system (FIS). The proposed expert and knowledge based framework includes the segmentation, feature extraction and classification of erythrocytes. First-order statistical analysis includes mean, standard deviation, skewness and kurtosis have been proposed as input parameters of FIS. The effectiveness of classifier is compared to find appropriate parameters for classification of normal cells and infected cells, both ring and trophozoite stages. The proposed method can provide 96.28% accuracy rate for binary classification of normal and infected cells. The results also yield 97.55% accuracy for ring stage classification, and 98.54% accuracy for trophozoite stage classification.