Comparative study of oral administration of Sacha Inchi oil extraction with erythromycin versus oral erythromycin on the treatment of Acne Vulgaris

This study was undertaken to evaluate the clinical efficacy, safety and satisfy by oral administration of Sacha Inchi oil extraction with oral erythromycin versus oral erythromycin on the treatment of Acne Vulgaris for 12 weeks. The randomized, controlled parallel dietary intervention study was performed in 32 participants with acne global severity grade 1–4, divided in 2 groups, oral Sacha Inchi oil extraction with oral erythromycin group and oral erythromycin group, respectively. This study decided to give intervention for 8 weeks and follow up at week 4, 8 and 12. Setting of preliminary study was one group of oral Sacha Inchi oil extraction with erythromycin. After 4 weeks of intervention, Sacha Inchi oil extraction with oral erythromycin, inflammatory and non-inflammatory acne lesions decreased significantly. Acne severity showed similar result. Patient subjective assessment of improvement showed similar result. Ne severe adverse effect of intervention was reported. This study shows for new evidence of Sacha Inchi oil extraction could be used as adjuvant treatment or supplement for acne treatment.