Novel applications of high-brightness LED in biomedical technology-development of photodynamic therapy of leukemia by LED

Light irradiation onto leukemia cells by LED were performed at 37 /spl deg/C using several sets of BIOLED placed in a CO/sub 2/ incubator under a fixed light intensity. We investigated the effect of light wavelength on the cell division. Irradiations onto cells were done for two kind of culture media: (1) with an addition of metal porphyrin which is used in photodynamic therapy (PDT) of cancers, and (2) without any additive.