Generation of high-pulse energy, wavelength-tunable, femtosecond pulse at 1600–2520 nm and its second-harmonic for multiphoton imaging

We demonstrate 1600-2520 nm wavelength-tunable, high energy soliton generation using a large-mode-area fiber pumped by a compact fiber source. Using second harmonic generation, we show their applications for in vivo multi-photon mouse brain imaging.