Characterizing absence epileptic seizures from depth cortical measurements

In this paper, we are going to localize the onset regions and investigate the dynamics of absence epileptic seizures using local field potential recording by depth electrode. We assume that there are some hidden states (under Markovian model) during the seizure and each spike of the seizure is generated when one of the states is activated. Each state is considered as the linear superposition of a few epileptic activities (substates) and each epileptic activity is described by two characteristics: 1) the spatial topography and 2) the temporal representation. Experimental results demonstrate the generality of the proposed model in characterizing absence epileptic seizures.