Multilayer formation during interfacial oscillation is essential for proper pulmonary surfactant function

Pulmonary surfactant physicochemistry is important in the proper mechanical function of the pulmonary system. Monolayer collapse and respreading are substantial contributors to the dynamic surface tension-area (S-A) loops. The authors compared experimental and theoretical studies of S-A behavior to discern the relevant physicochemistry in an oscillating bubble system. They found that secondary layer formation was highly dependent on the surfactant adsorption characteristics.