A Simulation Approach to Study the Effect of Ultrasonic MEMS Based Receiver for Blood Glucose Sensing Applications

The accurate measurement of glucose level in the blood is an important task to prevent the progression of chronic disease like diabetes mellitus. This article proposes a simulation based approach to evaluate the ZnO-based ultrasonic piezoelectric microelectronics mechanical systems (MEMS) receiver for blood glucose sensing applications. Prior to the fabrication of the proposed biosensor, a simulation study is conducted to avoid the dissipation of valuable time and cost. The potential of 1.6 V with a 350-MHz frequency is applied to the transmitter section that has been placed on the surface of blood sample with a cylindrical geometry having diameter and height of 1 and 10 mm, respectively. The surface and the radial displacement of the receiver section structure of the piezoelectric material with pressure and stress are studied in the blood medium. The simulation results reveal that, for different glucose density levels in the human blood, different pressure values are observed at the receiving end and that the respective pressure values are converted into voltages by using the piezoelectric principle. To verify the changes in the generated voltages, we have compared the glucose levels of blood samples using the proposed approach with the commercially available glucometer.