The relationship between mechanical and electrical dyssynchrony

The new QRS electrical depolarization map concept that is based on the processing of high frequencies in the QRS complex was introduced. The QRS electrical depolarization maps were derived from standard 12-lead ECG electrode placement and mechanical initiation maps were obtained using speckle tracking echocardiography of the left ventricle from 6 subjects suffering from left bundle branch block. The proposed method for assessing electrical depolarization showed to be highly reproducible in various passbands and also a high level of agreement between the shape of electrical depolarization and mechanical activation was demonstrated. The QRS electrical depolarization maps in frequencies ranging between 150-1000Hz could serve as a non-invasive and very easily accessible evaluation of the electrical properties of ventricular depolarization that initiates the mechanical action.