Electrochemical detection of a novel therapeutic compound for Schizophrenia

Detection of antipsychotic drugs are of great importance to inform the determination of optimum dosage for amelioration and remission rates, improving side effect profile and track patient compliance to the treatment. Up to date, various spectroscopic and chromatographic techniques have been used for this purpose but all methods present in the literature needed pre-treatment of the biological. Moreover, all these methods are not suitable for Point-of-care applications. In this work, for the first time, an electrochemical biosensor for the detection of a novel antipsychotic drug from serum has been designed with robust selectivity. The designed biosensor displays low nanomolar to micromolar detection range and, thank to his electrochemical method, provides a potentially suitable platform for future point-of-care applications.