"Smart" infusion apparatus for computation and automated delivery of loading, tapering, and maintenance infusion regimens of lidocaine, procainamide, and theophylline

"Smart" infusion apparatus now computes loading and tapering infusion protocols to achieve and maintain chosen serum lidocaine levels for patients, using a 2-compartment model of lidocaine. The apparatus, an HP-41CV hand calculator with appropriate interface, delivers the regimen automatically, starting up and controlling an IVAC Model 1500 volumetric infusion pump with its IVAC computer interface module. The device appears capable of similar computation and automated administration of many other drugs such as procainamide and theophylline. Preliminary upward adjustments of the regimen can also be made in the apparatus now, without recourse to an external computer.