Influence of time-of-flight and point spread function modeling in myocardial perfusion imaging of large patients

Using a medium and large sized anthropomorphic cardiac-torso phantoms we studied the effects of TOF and PSF to evaluate Rb-82 cardiac imaging of large patients. The reconstructed images were analyzed for recovery coefficient and RMS deviations on the polar plot data. Modelling PSF resulted in higher recovery coefficients while the reconstructions with TOF yielded reduced RMS deviations compared to non-TOF counterparts.