Research on glucose concentration sensing with single wavelength laser

Diabetes mellitus is one of major of ill health in the world. One of the popular topics in biomedical optics applications is using the near infrared spectra for non-invasive blood glucose measurement. Nonetheless, the most researches of blood glucose concentration measurement focus on the diffuse reflection either in domestic or overseas, the research of transmission is rare. In this paper, by the transmission experiment setup of non-invasive blood glucose measurement in our lab, the experiments of glucose concentration in glucose aqueous solutions based on Lambert-Beer theory are discussed. First, the optimal waveband (1310nm) is chosen for the non-invasive blood glucose concentration measurement set-up. And then, the hardware system which including laser diode, photoelectric detector and data processing module of this experiment set-up has been designed and some relevant experiments about glucose measurement are carried out. Finally, the optimal finger position of hand for human blood glucose concentration measurement is chosen. In a word, after some transmission experiments on glucose sensing, we could conclude that near infrared 1310nm light is proper for glucose concentration sensing in glucose aqueous solution, the index finger of hand is proper as the non-invasive blood glucose measurement and the transmission experiment set-up could be used for human blood glucose concentration sensing experiment later.