Analyzing the atrial depolarization wavefront triggered from sinus node and coronary sinus for identification of the arrhythmogenic substrate

The success rate of the cardiac ablation procedure to cure atrial fibrillation is moderate and depends on the experience and expertise of the physicians. It could be increased by precisely locating arrhythmogenic substrates. The aim of this work is to present a simple and feasible method to analyze intraatrial electrograms to identify the arrhythmogenic substrate on the atrium, under sinus rhythm and pacing sequences. The change in the depolarization wavefront propagation, resulting from consecutive triggering at a point in the coronary sinus (CS), can be an indication of the arrhythmogenic substrate. The region specific study enables the localization of critical sites in the patient specific atrial anatomy. This could aid the physicians in ascertaining the efficacy of cardiac therapies. In this work the point-to-point analysis of the intraatrial electrograms was carried out.