Multi-electrode arrays modified with bimetallic nanoparticles; electrical performance and neural signal recording

Microelectrode for neural signal recording was modified with Au-Pt nanoparticles (NPs). Impedance of Au-Pt NP-modified electrode was decreased by one order of magnitude compared with bare gold electrode which results in decreasing baseline noise and higher signal to noise than those of the Au NP-modified MEA. The reasonable neuron cell viability and spike recording capability were observed on Au-Pt NPs- modified electrode.