Sensing and quantification of salivary beta-amyloid peptides and protein sequencing for the saliva of normal and AD patients

Using salivary beta-amyloid peptides, the results to diagnose AD are briefly introduced. The quantity of AD peptides in the saliva of normal young man (nYM, normal elderly (nE) group and AD patients is measured in the range from very low concentration (~pg/ml) to high concentration (~ng/ml). For about 100 persons, nYM group and AD patients are below ~30pg/ml and ~ng/ml, respectively. In protein sequencing, other peptides are founded in the saliva that can distinguish between normal and AD patients.