Multifunctional smart lab-on-a-tube (LOT) probe for monitoring traumatic brain injury (TBI)

A novel multifunctional smart lab-on-a-tube (LOT) is described to continuously and accurately monitor multiple physiological, metabolic and electrophysiological parameters that are vitally important in guiding the care of patients with traumatic brain injury. In addition to measuring various crucial parameters, the newly developed probe allows for drainage of excess cerebrospinal fluid as a strategy to reduce intracranial pressure.