A macrophage simulator based on evolving cellular automata from video images

Macrophages are well known cells in biology. While macrophage plays an important role in the immune system, the behavior rules of macrophages are unknown. In our research, the final goal is to find action rules for behavior of macrophages. Our current aim is to develop a simulator which can reproduce the movement of macrophages. As the first step, we try to develop a simulator that can imitate macrophages' behavior in three-dimensional space. In order to develop a simulator, some movies of actual macrophages in live mice are used. After parsing the movies, we try to develop a simulator which can imitate behaviors as same results as the observed. Our proposed simulator is based on cellular automata which are evolved by genetic algorithms. From the results of our simulator, we can see that the artificial macrophages behave as the similar movement of actual macrophages.