Aminosilane-modified mesoporous oxidized silicon for in situ oligonucleotides synthesis and detection

Direct solid phase of oligonucleotides (ONs) requires high chemical stability of the support material. In this work, we investigate the passivation ability of porous oxidized silicon multilayered structures by two aminosilane compounds, APTES and APDMES, for the realization of a label-free ON optical biosensor.