Dual mode registration to improve estimation of perfusion parameters for ultrasound image sequences

The aim of this study is to present a new method for automatic motion compensation for ultrasound contrast imaging and to assess the impact on parametric perfusion imaging using linearized log-compressed data. Linear and non-linear ultrasound imaging are used for registration instead of one modality. The perfusion parameters estimated from the analysis of the time motion-compensated sequences of the contrast images show a great improvement in accuracy compared to the results obtained on uncompensated sequences and compensated sequences by linear images alone.