Prescreening seizure-like events in a rat model of epilepsy A: A 2D video processing method

Temporal lobe epilepsy is the most common cause of drug-resistant seizures. Electrical stimulation seems to be a promising alternative to the classical anteromesial temporal resection. Our work aims at improving and validating therapeutic approaches for treating temporal lobe epilepsy using high-frequency stimulation. The relative phase clustering index (rPCI) is used to describe the epileptogenicity of a brain region and seizure prediction. A 2D image processing algorithm is presented for facilitating the tedious and time consuming visual image inspection of long term video footage required to determine optimal electrical stimulation parameters. See our companion paper describing the 3D solution in this journal.