Antibacterial efficacy of zinc oxide (ZnO) nanoparticles on Vibrio anguillarum

Vibriosis is the most prevalent bacterial disease which causes high mortality among aquatic animals. Vibrio anguillarum is one of the main causative agents of Vibriosis. In the present study to control V. anguillarum, ZnO nanoparticles with average size of 50nm were synthesised using varying concentrations of starch (0.1%, 0.5% and 1%) as stabilising agent. Minimum inhibitory concentration (MIC) of the synthesised nano-ZnO was determined and compared with that of commercial nano-ZnO of 50 nm. Results showed that nanoparticles had varying antibacterial activity on V. anguillarum and nano-ZnO synthesised using 0.5% starch had the most efficient antibacterial activity against V. anguillarum with a MIC of 30μg/ml. The results concluded that nano-ZnO is an effective bactericidal agent against V. anguillarum.