A model of the entrainment of gastric electrical activity by electrical stimulation

Even though there has been an interest in employing pacemaker therapy for gastric motor dysfunction for about 40 years, gastric electrical stimulation (GES) is yet to move beyond laboratory experimentation. GES at near physiologic frequencies have been employed in dog and man with mixed results in eliciting native electrical control activity entrainment. There is also disagreement on its efficacy in enhancing gastric motility. Experimental determination of the optimum frequency is tedious. Technically, there is an infinite number of frequencies to test. The current study involved the development of a Matlab-based analytic model of gastric electrical stimulation GES.