Synthesis of antibacterial TiO2/PLGA composite biofilms

The main purpose of this study was to develop a TiO
₂
/PLGA composite biomaterial for artificial dressing applications. E. coli and S. aureus were used as biological indicators for the disinfection efficiency of the proposed TiO
₂
/PLGA composite. Various concentration ratios of TiO
₂
verse PLGA were implemented to optimize the disinfection efficiency of the composite biomaterial. Cell seedings of BECs and L929s on the TiO
₂
/PLGA composite biomaterial are further conducted to evaluate the feasibility of the TiO
₂
/PLGA composite biomaterial on wound healing applications. Experimental results illustrated that TiO
₂
/PLGA composite biofilms containing 10% of TiO
₂
nanoparticles revealed an effective antibacterial property but kept a comparatively low suppression on cell growth.