Multi-material paper-disc devices for low cost biomedical diagnostics

In this work we demonstrate novel, low cost, hybrid, polymer-paper disc devices for carrying out biomedical tests in resource-poor settings. The system combines the advantages of two major effects — sample transport in a paper membrane by capillary force and active rotational flow control by centrifugal force. Capabilities of the paper disc system include but are not limited to spatiotemporal flow control, pre-storage of reagents and integrated colorimetric indicators all suitable for performing multiple-step bioassays.