A universal coulometric nanotitrator

This paper reports the fabrication of a coulometric nanotitrator and its application for four different types of titrations: precipitation, complex-formation, redox and acid-base nanotitrations. This simple device, composed of planar electrodes in a microchannel, gives very reproducible results and yields a linear dependence between the analyte concentration and the equivalence time for concentrations up to 10/sup -2/ M of analyte.