A micro-planar amperometric glucose sensor unsusceptible to interference species

The authors describe an amperometric glucose sensor characterized by a rapid response, a wide measuring range, and practical immunity to interference species. Sensors coated with acetylcellulose, Nafion/sup TM/, and polydimethylsiloxane have been developed to prevent interference species. Tests of the sensor demonstrate its imperviousness to the effects of ascorbic acid (<11.4 mM), uric acid (<0.30 mM), and acetaminophen (<0.40 mM), as well as its determining glucose concentrations ranging from 0.56 to 33.3 mM, and its capacity to reach steady-state response within 10 seconds.