A developed microfluidic system with model reference adaptive control

A developed microfluidic system which is actuated by EO (electroosmotic) actuators was presented toward biomedical system and drug delivery systems. The classical structure, which consists of an actuating unit, chambers and rectifiers, has been employed in the design. The EO actuators with the impulse input make the polydimethylsiloxane (PDMS) diaphragm which separates the two chambers reciprocate. So the working liquid can be pumped from inlet to outlet. Due to the large deflections of the PDMS diaphragm, the device is completely self-filling and able to pump liquid even operated in vertical situation. By using the indirect pumping mechanisms, the EO actuator can be used more widely without considering the properties of the working liquid. In order to find the characteristic of the microfluidic system, the Bouc-Wen model was used to model it. Based on this model, the model reference adaptive control (MRAC) method was used to obtain the stable flow rate, because of the uncertain parameter. And some simulations were manipulated to show the controlling results of the MRAC which is used in the microfluidic system. These researches demonstrate the microfluidic system with MRAC performance and ability to deliver the fluid and drugs to biomedical systems.