Change points in DNA coding sequences

We investigated genes that contain change points of triplet periodicity. The algorithm for detection of TP splicing of nucleotide sequences has been developed. Gene sequences from KEGG-48 databank were analyzed with a purpose of searching for genes with a TP change point. This change points were found in 311221 genes (~8% from the total number of genes in KEGG-48). We showed that the repetitive or low-complexity sequences are not cause of these events. We suppose that the TP change points may indicate fusion of genes or domains with different types of TP.