Comparison of spectrally sparse excitation signals for fast bioimpedance spectroscopy: In the context of cytometry

This paper presents a comparative study of multifrequency excitation signals that are suitable for fast bioimpedance spectroscopy. If properties of an object are changing fast or if the objects are moving fast, e.g. cells flowing within microfluidic channels, the excitation signal should cover the frequency range of interest in short timeframes. However, since shorter signals carry less energy this reduces the signal-to-noise ratio performance. To enhance performance, it is essential to concentrate the signal's energy right on the specific frequencies of interest. Taking into account properties of the biological matter allows us to use more efficient spectrally sparse excitation signals. We also demonstrate that properly designed binary multifrequency excitation signals offer better performance in comparison to multisinewave signals.