Preparation and in vivo anti-HPV effect of the herbal colloid lotion (MPC) on 49 cases of Condyloma Acuminatum patients

MPC lotion is a kind of colloid solution extracted from several materials of Chinese herb medicines. The anti-human papilloma virus (HPV) activity of MPC lotion on Condyloma Acuminatum (CA) patients was investigated. In treated group, the verrucae of the CA patients were wiped out with a sterile cotton tip applicator dipped with MPC lotion and were put in the vagina as suppository once a day, for 7 days. In the control group, CO
2
laser therapeutic equipment and 1, 000, 000 IU of α-interferon were used to remove the verruvae. Results showed that no relapse patient was found in the MPC treated group, but 19 cases (63.4%) was relapsed in the control group after 8 months. The relapse rate in MPC group was significantly lower (x
²
=17.926, P < 0.01) than that in the control group. MPC lotion was an effective, safe, feasible and economical anti-HPV natural health product for curing CA.