A graphene-based microelectrode for recording neural signals

We designed, fabricated and tested a novel prototype neural interface using two-dimensional single-atom-thick graphene as microelectrode for neural applications. The cytotoxicity indicated a satisfactory biocompatibility and non-toxicity. The treatment graphene with steam plasma improved the biological properties. The action potentials of lateral giant (LG) nerve fiber of the escape circuit of an American crayfish had a ratio of signal to noise (SNR) as great as 30.2±2.45 dB.