The cooperative transport mechine of protein motors under the electrostatic interaction

Kinesin transports cargos along the microtubule and myosin along the actin. The experiment finds that when kinesin-2 and myosin V transport a same cargo together, they act as tethers to enhance each others' processivity because of the electrostatic interaction between them and the tracks. Here, on the basis of the experiment, the electrostatic interaction between the protein and the track is considered, and the effects of the electrostatic interaction, the rate of dissociation, and the rate of re-combining on the run length of the motor respectively are studied. The results explain qualitatively the experimental phenomena.