Fractal properties of epileptic local field potentials recorded from different layers of the frontal cortex using a chronically implanted laminar microelectrode in humans

In this study we analyzed monofractal and multifractal properties of epileptic local field potentials recorded from different layers of the frontal cortex. Seven seizures of two patients suffering from drug resistant frontal lobe epilepsy were assessed. We found drastic changes of fractal properties during the seizures. Distinct gradual changes of these properties were present before and after the ictal states. Moreover, laminar characteristics of the estimated measures were observed. Our results might be used to reveal the mechanisms related to the dynamics of epileptic seizures and perhaps to develop a seizure detection/prediction algorithm.