Wettability Switching Technique of a Biocompatible Polymer

In this paper we present data of protein adsorption on topographically altered active polymeric films, investigated using atomic force microscopy (AFM), fluorescence microscopy, and contact angle measurement. The surface wettability of biocompatible polypyrrole (PPy) films was altered via low applied currents, and we have demonstrated switchable hydrophobic-hydrophilic surfaces, used as protein adhesion substrates. The preliminary results showed that both BSA and fibronectin have higher affinities for and adhere preferentially to hydrophobic surfaces.