Blood glucose-insulin regulation and management system using MATLAB/SIMULINK

Biomedical signal processing has exponentially been expanding and demanding area for research and subsequent applications in its respective quarters. Exploration on diabetes is one of the main segments of this area which is being addressed for the decades. One of the main functions of the pancreas is to regulate glucose concentration in blood through release of the enzyme insulin. Some theoretical analysis of the control of blood glucose level in diabetic individuals is undertaken using a simple mathematical model of the dynamics of glucose and insulin interaction in the blood system developed by Stolwijk and Hardy dynamic model [1]. This paper is focused to envisage the regulation and management of the concentration of glucose and insulin in the blood of a diabetic. The model was modified by adding a term for exogenous insulin infusion. Using this model, a closed-loop feed back system which regulates and manages the blood glucose-insulin has been designed, implemented and analyzed using Matlab/Simulink. This system imitates as an artificial pancreas on day-to-day basis. A time-consuming and tedious series of diabetes experiments was carried out and results were analyzed on the basis of medical parameters. The obtained results showed significant regulation and management of the glucose-insulin delivery in the blood. Hence, we are reasonably confident of having contribution in the subject area.