Lab-on-a-chip sensor for assessment of manganese exposure

In this paper, we describe development of a point-of-care sensor for rapid electrochemical measurement of biological exposure to manganese (Mn). The sensor was fabricated using bismuth as working electrode and Ag/AgCl as integrated reference. Electrochemical performance of the lab-on-a-chip sensor was characterized by measuring oxidation reduction potential (ORP) of reference solutions and square wave stripping voltammetry (SWSV) of Mn standard solutions. The envisioned sensor will permit workers quickly and safely monitor their biological dose of Mn on the jobsite, minimizing exposure and ensuring worker safety.